Imani Ibrahim, a 33-year-old Chicago-based clinical social worker, became ill in January 2020. “I was very sick for a few days with flu-like symptoms. At that point, COVID-19 had not yet become a big outbreak, and I didn’t know what I had,” she said. Two months later, she went to […]
Healthcare providers should always obtain a travel history from febrile patients. Fever in a person who has recently traveled in a malaria-endemic area should always be immediately evaluated using the appropriate diagnostic tests for malaria. Diagnosis Rapid and accurate diagnosis of malaria is integral to the appropriate treatment of affected […]
In nature, microorganisms use CRISPR (clustered regularly interspaced palindromic repeats) and CRISPR-associated (Cas) proteins for antiviral immunity through recognition and destruction of specific DNA sequences. Over the past decade, CRISPR genome editing has been developed to create transformative technologies to treat, cure, and prevent human disease. How CRISPR Works CRISPR […]
Guideline title ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections Release date May 18, 2021 Prior version 2013 Developer American College of Gastroenterology (ACG) Funding source ACG Target population Adults with suspected or diagnosed Clostridioides difficile infection (CDI) Major recommendations Initial CDI should be treated with vancomycin or fidaxomicin (strong recommendation; moderate-quality evidence). Metronidazole may be considered […]
Safe, effective treatment options are urgently needed for those with tuberculosis caused by drug-resistant Mycobacterium tuberculosis. In a recent study in South Africa, the combination of bedaquiline, pretomanid, and linezolid (1200 mg linezolid daily; BPL 1200) for 26 weeks yielded a microbiologic cure rate over 90%, but with significant linezolid toxicity […]
Neither metformin, ivermectin, nor fluvoxamine had any impact on reducing disease severity, hospitalization, or death from COVID-19, according to results from more than 1,000 overweight or obese adult patients in the COVID-OUT randomized trial. However, metformin showed some potential in a secondary analysis. Early treatment to prevent severe disease remains a goal in managing […]
Black and Hispanic patients were respectively 29% and 23% less likely than white patients to have their treatment eligibility recognized by pulse oximetry A retrospective analysis of more than 7,000 patients with COVID-19 found that pulse oximeter devices—tools that measure oxygen levels in the blood and that are used in […]
Healthcare providers should always obtain a travel history from febrile patients. Fever in a person who has recently traveled in a malaria-endemic area should always be immediately evaluated using the appropriate diagnostic tests for malaria. Diagnosis Rapid and accurate diagnosis of malaria is integral to the appropriate treatment of affected […]
The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is unclear. METHODS We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults […]
New research suggests that alpha-1 antitrypsin could be an effective option for treating those with COVID-related acute respiratory distress syndrome (ARDS). In their study, published in the journal Med, researchers from RCSI University of Medicine and Health Sciences and Beaumont Hospital Dublin investigated the effects of using the anti-inflammatory protein alpha-1 antitrypsin […]
