Medical Health Cluster

Thrombosis

Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study

Abstract Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19. Design Self-controlled case series and matched cohort study. Setting National registries in Sweden. Participants 1 057 174 people who tested positive for SARS-CoV-2 between 1 February 2020 and 25 May 2021 in Sweden, matched on age, sex, and county of […]

Read More

Medically Ill Hospitalized Patients for COVID-19 Thrombosis Extended Prophylaxis With Rivaroxaban Therapy – MICHELLE

Contribution To Literature: The MICHELLE trial showed that rivaroxaban after hospitalization for COVID-19 improved clinical outcomes without increasing bleeding. Description: The goal of the trial was to evaluate rivaroxaban compared with control among patients discharged after hospitalization for coronavirus 2019 (COVID-19) infection. Study Design Randomization Parallel Participants discharged after COVID-19 […]

Read More

Cerebral Venous Thrombosis

Cerebral venous thrombosis is characterized by infarction with focal neurologic deficits and increased intracranial pressure. As a very rare complication of some vaccines against Covid-19, the disorder is accompanied by disseminated intravascular coagulation and hemorrhage. https://www.nejm.org/doi/full/10.1056/NEJMra2106545?fbclid=IwAR0HpD7KqyWNHPu44xdje7VcAfU58ffkTOKCA6goKsxuR6WtH_nYSvnOT20 Créditos: Comité científico Covid

Read More

Pulmonary immuno‑thrombosis in COVID‑19 ARDS pathogenesis

  Pulmonary immunothrombosis critical in #COVID19 #ARDS pathogenesis:*local endotheliopathy due to specific deleterious effects of #SARSCoV2 infection upon pulmonary endothelial cells* thrombocytopathy: multifactorial platelet activation* enhanced vascular permeability, facilitating leucocyte extravasation/exacerbating alveolar infammation & edemanet effect? generation of platelet–fibrin rich thrombi disseminated throughout pulmonary vasculature.Complex multifactorial mechanisms involved, unlikely one-size-fits-all approach will be enough: […]

Read More