Small airway disease with air trapping appears to be a long-lasting sequela of SARS-CoV-2 infection, according to a prospective study that compared 100 COVID-19 survivors who had persistent symptoms and 106 healthy control persons. “Something is going on in the distal airways related to either inflammation or fibrosis that is […]
Question Among patients at risk of disease progression, does early treatment of mild to moderate COVID-19 with the neutralizing antibody sotrovimab prevent progression to severe disease? Findings In this randomized clinical trial of 1057 participants, treatment with a single intravenous dose of sotrovimab, compared with placebo, resulted in a statistically significant reduction […]
INTERVIEW BY STEPHANIE DESMON For many immunocompromised patients, the regular two-dose COVID-19 vaccine regimen—and in some cases, even a third dose—didn’t provide sufficient immune protection. As a result, approximately 5 to 7 million immunocompromised people living in the U.S. have been struggling for over a year with how they will […]
A new survey finds most Americans are in favor of allotting “the last ICU bed” to the patient with the highest probability of surviving COVID-19. Responses from 2,000 respondents from the nationally representative YouGov internet panel also show that, for the most part, people were not swayed by the age […]
The following statement is an updated version of the statement that the COVID-19 Treatment Guidelines Panel (the Panel) released on December 30, 2021. This update addresses the fact that the B.1.1.529 (Omicron) variant of concern (VOC) is now the dominant SARS-CoV-2 variant in all 10 of the Department of Health and […]
Low-dose rivaroxaban at discharge prevented some venous thromboembolism events at 1 month for high-risk patients. Therapeutic anticoagulation after hospital discharge does not benefit moderate-risk patients recovering from COVID-19 (NEJM JW Gen Med Aug 1 2021 and Lancet 2021; 397:2253), but whether high-risk patients might benefit is unclear. Brazilian investigators enrolled 320 patients (from […]
In Maryland, Covid patients are now filling 42 percent of the state’s adult intensive care unit beds, the highest rate in the nation. In Connecticut, 32 percent of adult ICU beds are filled with Covid patients, more than double the rate four weeks ago. These are just two states where […]
The amount of a SARS-CoV-2 genetic material—viral RNA—in the blood is a reliable indicator in detecting which patients will die of the disease, a team led by Université de Montréal medical professor Dr. Daniel Kaufmann has found. The finding is published today in Science Advances. Kaufmann and his team did the work at […]
In June, Gerald Bock, MD, a dermatologist in central California, instituted a new office policy: He would not be seeing any more patients who remain unvaccinated against COVID-19 in his practice. Dr Joseph Eastern “[It is] the height of self-centered and irresponsible behavior,” he told me. “People who come in […]
Doctors in Northern Ireland have reported facing increasing cases of aggression from patients and hospital visitors refusing to wear face masks during NHS appointments. The British Medical Association said there was also growing resistance to being tested for COVID before attending routine appointments or going to emergency departments. Dr David Farren, deputy chair of […]
