France — During a round-table discussion at the French Senate, specialists in infectious disease and epidemiology presented their thoughts on what might happen after the Omicron wave passes. Will COVID become an endemic disease, or will new, worrisome variants emerge? Using various types of data, the experts shared their views which, […]
The currently available two-dose COVID-19 vaccines were not effective in preventing symptomatic disease caused by the Omicron variant, as determined on the basis of data from more than 800,000 Omicron-infected individuals. Early laboratory data suggested a substantially lower neutralizing antibody response to the Omicron variant compared to both the original […]
BACKGROUND A rapid increase in coronavirus disease 2019 (Covid-19) cases due to the omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 in highly vaccinated populations has aroused concerns about the effectiveness of current vaccines. METHODS We used a test-negative case–control design to estimate vaccine effectiveness against symptomatic disease […]
Desde su aparición a fines de 2019 hasta la fecha, el coronavirus ha afectado a una gran parte del mundo. Una gama de síntomas que varía de persona a persona, una fase de COVID prolongada o posterior a COVID y muchas otras gravedades están asociadas con la infección viral, entre […]
The omicron wave that assaulted the United States this winter also bolstered its defenses, leaving enough protection against the coronavirus that future spikes will likely require much less — if any — dramatic disruption to society. Millions of individual Americans’ immune systems now recognize the virus and are primed to fight it […]
Viruses constantly evolve over time through mutations. This can result in new variants, like the fast-spreading Omicron variant of SARS-CoV-2. Omicron has a large number of mutations in its spike protein, which makes it more able to latch onto and infect cells. As a result, Omicron spreads more easily and causes […]
What is already known about this topic? CDC conducts genomic surveillance to track SARS-CoV-2 variants in the United States. What is added by this report? CDC’s SARS-CoV-2 genomic surveillance has been expanded to incorporate sequence data from public repositories and to produce weighted estimates of variant proportions at the jurisdiction […]
The SARS-CoV-2 Omicron variant has become the dominant infective strain. We report the structures of the Omicron spike trimer on its own or in complex with ACE2 or an anti-Omicron antibody. Most Omicron mutations are located on the surface of the spike protein, which change binding epitopes to many current […]
Los datos más recientes de la Agencia de Seguridad Sanitaria del Reino Unido (UKHSA) sugieren que la subvariante BA.2, un linaje descendiente de la variante B.1.1.529, puede ser incluso más transmisible que la variante original.[1] Pero la buena noticia es que las vacunas actuales parecen ofrecer el mismo nivel de protección contra […]
We now know a lot more about how COVID-19 affects our body, from the contagious phase after the initial infection and symptom onset, through to either recovery or death. But as researchers are discovering, the road to recovery is complicated for a seemingly random subset of people. Known as “long […]
