Key Points Question Does adding ivermectin, an inexpensive and widely available antiparasitic drug, to the standard of care reduce the risk of severe disease in patients with COVID-19 and comorbidities? Findings In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during […]
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The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is unclear. METHODS We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults […]
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Ivermectin, an anti-parasitic drug that became popular as an alternative treatment for COVID-19, showed no signs of quelling the disease or reducing patients’ risk of hospitalization, according to results from a large clinical trial published in The New England Journal of Medicine. The findings pretty much rule out the drug as a treatment […]
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The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is unclear. METHODS We conducted a double-blind, randomized, placebo-controlled, adaptive platform trial involving symptomatic SARS-CoV-2–positive adults […]
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The anti-parasitic drug ivermectin does not reduce hospitalizations of people infected with COVID-19, according to a large study conducted in Canada. Researchers at McMaster University in Ontario studied around 1,358 COVID patients who were at risk for severe disease because they had diabetes or other conditions, The Wall Street Journal reported. Half the patients […]
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COVID-19. We’ve been living with it for what sometimes seems like forever. Given the number of deaths that have occurred from the disease, it’s perhaps not surprising that some consumers are turning to drugs not approved or authorized by the Food and Drug Administration (FDA). One of the FDA’s jobs is to […]
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Question Does adding ivermectin, an inexpensive and widely available antiparasitic drug, to the standard of care reduce the risk of severe disease in patients with COVID-19 and comorbidities? Findings In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first […]
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It was a late September day in 2019 when I first learned about ivermectin. I had just started my postdoctoral position at UCLA studying the human-infective threadworm Strongyloides stercoralis. Standing in our lab’s parasite room in my disposable lab coat, my hands double-gloved up to my elbows and my mask and […]
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The authors of a study purportedly showing that ivermectin could treat patients with SARS-CoV-2 have retracted their paper after acknowledging that their data were garbled. The paper, “Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon,” […]
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Some authors of a widely reported meta-analysis of ivermectin studies that was flagged for including potentially fraudulent research have just posted a re-analysis on a preprint server — and ivermectin’s seemingly beneficial effects disappeared as trial quality went up. For the re-analysis, Andrew Hill, PhD, of the University of Liverpool in England, and colleagues […]
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