The U.S. may see as many as 140 million new COVID-19 infections in the first two months of 2022, according to new modeling data from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington’s School of Medicine. After revising their modeling data to include updated information about the omicron variant, researchers […]
Interferons are innate and adaptive cytokines involved in many biological responses, in particular, viral infections. With the final response the result of the balance of the different types of Interferons. Cytokine storms are physiological reactions observed in humans and animals in which the innate immune system causes an uncontrolled and […]
Widespread infection in white-tailed deer has created concern about the possibility of mutated versions of the virus spreading back to humans. What to know: A study of coronavirus infections among white-tailed deer in Iowa found that about 80% of deer sampled across the state between April 2020 and January 2021 […]
The persistent syndrome of COVID-19 after-effects known as long COVID can develop after “breakthrough” infections in vaccinated people, a new study shows. Researchers at Oxford University in the UK reviewed data on nearly 20,000 U.S. COVID-19 patients, half of whom had been vaccinated. Compared to unvaccinated patients, people who were […]
Waning immunity to SARS-CoV-2 vaccination, coupled with the highly transmissible Delta variant and the end of mask mandates, likely contributed to a resurgence of SARS-CoV-2 infections among a highly vaccinated group of healthcare workers in California, according to a report released Wednesday. However, the “headline here needs to be nuanced,” […]
Eric Topol was worried when he first saw images of the lungs of people who had been infected with COVID-19 aboard the Diamond Princess, a cruise ship that was quarantined off the coast of Japan in the earliest weeks of the pandemic. A study of 104 passengers found that 76 […]
Pfizer announced Thursday that it will seek US Food and Drug Administration (FDA) authorization for a booster shot of its COVID-19 vaccine as the company acknowledges its two-dose vaccine has shown waning effectiveness against the Delta variant. In a statement, the company said it will seek an emergency use authorization […]
A 2-dose regimen of the BNT162b2 vaccine (Pfizer-BioNTech) against SARS-CoV-2 was authorized in December 2020 based on reported 94.8% efficacy.1 Although an association between vaccination and a reduction in symptomatic disease has been well described, an association with asymptomatic infection remains unclear.2,3 Methods In March 2020, St Jude Children’s Research Hospital […]
Summary Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are of clinical concern. In a cohort of 417 persons who had received the second dose of BNT162b2 (Pfizer–BioNTech) or mRNA-1273 (Moderna) vaccine at least 2 weeks previously, we identified 2 women with vaccine breakthrough infection. Despite evidence of […]
Vaccination with the Pfizer or Moderna vaccine reduces infections by 90%, while a single dose confers 80% protection, shows a study led by the US Centers for Disease Control and Prevention (CDC) that followed essential workers through the worst months of the pandemic. The study is one of a small […]
