A Better Treatment Option for Drug-Resistant Tuberculosis

Safe, effective treatment options are urgently needed for those with tuberculosis caused by drug-resistant Mycobacterium tuberculosis. In a recent study in South Africa, the combination of bedaquiline, pretomanid, and linezolid (1200 mg linezolid daily; BPL 1200) for 26 weeks yielded a microbiologic cure rate over 90%, but with significant linezolid toxicity […]