(Reuters Health) – Patients with rheumatic and musculoskeletal diseases may be less likely to mount an antibody response to the Johnson and Johnson (J&J) COVID-19 vaccine compared with those who get an mRNA-based vaccine, a new study suggests. Data from a prospective cohort of 1,039 patients with rheumatic and musculoskeletal […]
An injected monoclonal cocktail given to household contacts of patients with COVID-19 was 81% effective. Postexposure prophylaxis with immunoglobulins has been the standard of care for many infectious diseases; thus, an effective immunoglobulin preparation for COVID-19 would provide a powerful new public health approach to controlling the current pandemic. Researchers […]
A combination of two monoclonal antibodies given as a subcutaneous injection prevented COVID-19 in patients at a high risk of infection due to household exposure, according to results of a randomized, double-blind, placebo-controlled clinical trial published online August 4 in the New England Journal of Medicine. The cocktail of the monoclonal antibodies casirivimab and […]
More than nine in 10 UK adults have antibodies to SARS-CoV-2 following one dose of the Oxford AstraZeneca or Pfizer BioNTech vaccine, while almost everyone does after a second dose, preliminary data suggest.1 A study of 8517 adults in England and Wales by University College London’s Virus Watch project found […]
Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. JOHN WHYTE: Welcome, everyone. I’m Dr. John Whyte, Chief Medical Officer at WebMD, and you’re watching Coronavirus in Context, where we try to break down what’s happening with coronavirus and how it impacts your life. We’ve been talking a […]
Créditos: Comité científico Covid
Abstract Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine induced immunity. Here we compared humoral and cellular responses against SARS-CoV-2 VOC in subjects immunized with the DNA vaccine, INO-4800. INO-4800 vaccination induced neutralizing antibodies against all variants […]
Educational Impact Challenge The goal of this activity is to increase clinicians’ knowledge and understanding of how neutralizing monoclonal antibodies function to both treat patients with COVID-19 and prevent disease in others. Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after […]
(Reuters) – Antibodies induced by the Pfizer/BioNTech and Moderna vaccines and the antibody therapy from Regeneron Pharmaceuticals all are able to neutralize a coronavirus variant on the rise in New York, lab experiments show. The New York variant contains mutations – E484K, S477N and D235G – that experts feared might […]
More than three quarters of Wuhan residents who tested positive for SARS-CoV-2 antibodies had experienced no covid-19 symptoms and just under half developed long lasting neutralising antibodies, show results from the first long term seroprevalence study from the epicentre of the outbreak in China.1 Researchers tested 9542 people from 3556 […]
