The COVID-19 mRNA vaccines’ 2-dose primary series appeared to provide less protection against hospitalization from Omicron variant infections than Alpha and Delta infections, according to a recent study. A booster dose, however, was associated with increased effectiveness against Omicron hospitalizations at the same high levels achieved against earlier variants with 2 […]
Summary What is already known about this topic? Persons with previous SARS-CoV-2 infection have some protection against reinfection leading to hospitalization, but there is limited evidence regarding the additional benefit of vaccination among these persons. What is added by this report? Among persons with previous infection, COVID-19 mRNA vaccination provided […]
Question What are the neuropathologic changes of COVID-19 in the olfactory region? Findings In this cohort study of 23 deceased patients with COVID-19 and 14 matched controls, more severe axon pathology, axon losses, and microvascular pathology were noted in olfactory tissue from patients with COVID-19 than that from the control individuals. The […]
Thousands more vulnerable people are eligible to receive the UK’s second antiviral Paxlovid, which has been added to the PANORAMIC national study. Paxlovid reduced the risk of hospitalisation or death by 88% in clinical trials and is already available directly through the NHS to highest-risk patients The UK has procured […]
One trial. Over 47,000 participants. Nearly 200 hospital sites, across six countries. Ten results. Four effective COVID-19 treatments. And behind them all, an army of countless researchers, doctors, nurses, statisticians and supporting staff. On the second anniversary of its official launch, the Randomised Evaluation of COVID-19 Therapy (RECOVERY) remains an […]
Abstract Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19. Design Self-controlled case series and matched cohort study. Setting National registries in Sweden. Participants 1 057 174 people who tested positive for SARS-CoV-2 between 1 February 2020 and 25 May 2021 in Sweden, matched on age, sex, and county of […]
In its latest report, the Office for National Statistics (ONS) has updated the ethnic contrasts in deaths involving COVID-19 highlighting how patterns in rates of deaths involving COVID-19 between ethnic groups has changed over the course of the coronavirus pandemic. Their new report covers the period from January 10, 2022 to […]
Una de las principales características de todos los virus es su tendencia a la mutación. En ocasiones estos cambios son mínimos y no generan afectaciones mayores. En cambio, en otras son demasiadas las modificaciones y eso aumenta el peligro. Por lo mismo, desde que se identificó el SARS-CoV-2 se alertó […]
Federal regulators announced Tuesday that GlaxoSmithKline’s COVID-19 drug should no longer be used because it’s likely ineffective against BA.2, the Omicron subvariant that now accounts for most new cases in the U.S., the Associated Press reports. The FDA announced that the antibody drug sotrovimab is no longer authorized to treat patients in U.S. […]
Practice Essentials Tinnitus is the perception of sound in the head or the ears. The term tinnitus derives from the Latin word tinnire, meaning to ring. Typically, an individual perceives the sound in the absence of outside sounds, and the perception is unrelated to any external source. Sound that only the patient […]
